XEMIS2 Liquid Xenon Compton Camera for Small Animal 3γ Medical Imaging: Scintillation Light Measurement - IMT Atlantique Accéder directement au contenu
Communication Dans Un Congrès Année : 2019

XEMIS2 Liquid Xenon Compton Camera for Small Animal 3γ Medical Imaging: Scintillation Light Measurement

Julien Bert
Thomas Carlier
Michel Cherel
Debora Giovagnoli
  • Fonction : Auteur
Francoise Kraeber-Bodere
  • Fonction : Auteur
Dimitris Visvikis

Résumé

An innovative XEnon Medical Imaging System, named XEMIS2, consisting of a liquid xenon (LXe) Compton camera, is developed to image small animal with 3γ imaging technique. The main objective of XEMIS2 involves the 3D localization of a radiopharmaceutical labeled with a specific radionuclide 44 Sc and the lessening of the administered radiotracer activity while preserving the image quality in oncology diagnosis. XEMIS2 is a monolithic single-phase detector with a large axial Field Of View (FOV), handling up to nearly 200 kg of ultra-high-purity liquid xenon. The XEMIS2 facility has been successfully conceived and developed at the SUBATECH laboratory. In XEMIS2, the scintillation signals provide the γ-rays interaction time. Furthermore, it is possible to pre-localize the γ-rays interactions spatially and then achieve the virtual fiducialization of the active volume by matching the scintillation signals with the ionization signals. In order to measure scintillation light, we distribute a set of PhotoMultiplier Tubes (PMTs) around the surface of the active area. Besides, a self-triggered scintillation light detection chain has been specially developed for XEMIS2 to carry out continuous data taking with negligible electronics dead-time. It is currently calibrated in the prototype XEMIS1. The calibration results indicate that the dedicated detection chain has a good performance in scintillation light measurement. XEMIS2 is recently under construction in a small animal medical imaging center CIMA, for further preclinical studies. I. INTRODUCTION OR the past few decades, nuclear medical imaging has extended from organ imaging for tumor localization of a variety of diseases and proven remarkable value in oncology Manuscript received
Fichier principal
Vignette du fichier
nssmic19_zhu.pdf (509.56 Ko) Télécharger le fichier
Origine : Fichiers produits par l'(les) auteur(s)

Dates et versions

hal-03044142 , version 1 (15-12-2020)

Identifiants

Citer

Yuwei Zhu, Stephane Acounis, Nicolas Beaupere, Jean-Luc Beney, Julien Bert, et al.. XEMIS2 Liquid Xenon Compton Camera for Small Animal 3γ Medical Imaging: Scintillation Light Measurement. 2019 IEEE Nuclear Science Symposium and Medical Imaging Conference (NSS/MIC), Oct 2019, Manchester, United Kingdom. pp.1-4, ⟨10.1109/NSS/MIC42101.2019.9059638⟩. ⟨hal-03044142⟩
191 Consultations
183 Téléchargements

Altmetric

Partager

Gmail Facebook X LinkedIn More